CAS:1256585-15-5|Alectinib-d8

【產品介紹】：

化學名稱：Alectinib-d8
同義名稱：9-Ethyl-6,11-dihydro-6,6-dimethyl-8-[4-(4-morpholinyl-2,2,3,3,5,5,6,6-d8)-1-piperidinyl]-11-oxo-5H-benzo[b]carbazole-3-carbonitrile
CAS號：1256585-15-5
Alternate CAS #
1256580-46-7
分子式：C??H??D?N?O?
Appearance:White to Off-White Solid
Melting Point:>265°C (dec.)
分子量：490.67
Storage:4°C, Inert atmosphere
Solubility:DMSO (Slightly), Methanol (Slightly, Heated, Sonicated)
產品類別：Standards; Isotopic Labeled Analogues; Pharmaceutical/API Drug Impurities/Metabolites;
產品應用：Alectinib-d8 is the labelled analogue of Alectinib (C183365, HCl), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth. Also is an intermediate of Alectinib (C183360), a highly selective and potent anaplastic lymphoma kinase (ALK) inhibitor capable of blocking the resistant gatekeeper mutant, which results in reduced cell growth.
參考文獻：Sakamoto, H., et al.: Cancer Cell., 19, 679 (2011); Kinoshita, K., et al.: Bio-org. Medn., 20, 1271 (2012);
To ensure the stability of our products, the efficient express delivery service will be used. We also guarantee that the products will be shipped in the box with layers of tapes to protect them against damage. The extremely low temperature products will be wrapped with dried ice, and the low temperature products will be delivered with ice bags. As for the products stored at room temperature, they will not be packed with ice bags or dried ice. Delta is committed to providing cost-effective products that facilitate drug delivery with our customers.